Doctors give unbiased, trusted information on whether Sertraline can cause or treat Muscle Weakness: Dr. Kent on zoloft muscle weakness: Is a newer atypical antidepressant. While trazodone, a nontricyclic antidepressant, can cause headaches, twitching muscles, dry mouth, nausea, but not joint or muscle weakness. These side effects occur. Note: This document contains side effect information about sertraline. Some of the dosage forms listed on this page may not apply to the brand name Zoloft. Zoloft is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Summary. Weakness is found among people who take Zoloft, especially for people who are female, 60+ old , have been taking the drug for 1 month, also take medication Xanax, and have Pain. Zoloft is an SSRI (selective serotonin reuptake inhibitors) antidepressant prescribed for the treatment of depression, obsessive compulsive disorder , panic disorder, posttraumatic stress disorder , social anxiety disorder, and premenstrual dysphoric disorder. Zoloft is available as a generic drug. Because Zoloft leaves your body so quickly, stopping it too abruptly can cause discontinuation syndrome to develop. Among the symptoms that may be experienced are nausea, tremor, dizziness, muscle pains, weakness, insomnia, and anxiety. Zoloft (generic name: sertraline) is part of a large family of antidepressants known as SSRI’s (selective serotonin reuptake inhibitors) which increase serotonin in the brain. Zoloft And Muscle Weakness | NoPrescriptionPharmacy. Complete Zoloft And Muscle Weakness Packaging and Shipping Supplies, Inc (Complete Packaging), is a leading provider of integrated supply, procurement and logistics solutions through distribution of a diverse range of products and services worldwide. Find information about common, infrequent and rare side effects of Zoloft Oral. Zoloft use in the third trimester may increase a baby's chance of developing persistent pulmonary hypertension which can cause breathing problems. In addition, third-trimester use of Zoloft may cause neonatal withdrawal symptoms like temperature instability, feeding problems, and constant crying.